No, the COVID-19 Vaccine does not cause infertility.

There are false rumors circulating that the COVID-19 vaccine causes infertility in women. None of these are true. Because pregnant and breastfeeding women were excluded from the Phase III trials of both the Pfizer and Moderna vaccines, we lack specific data on safety and efficacy in these groups. Women’s concern about potential risk of vaccination is understandable--particularly when social media is full of posts talking about the risk of infertility.  

However, there is no evidence of any risk of infertility, early pregnancy loss, or other pregnancy risks among women who have been vaccinated or who have had COVID-19 infection. Nor is there any mechanism by which the Pfizer of Moderna vaccines could cause infertility. In fact, the women who got pregnant during the course of the Pfizer study had normal pregnancies.

One false rumor is that the antibody to the coronavirus spike protein (found in both people who have recovered from COVID-19 and vaccinated people) reacts with a placental protein called syncytin-1. This rumor is false. Scientists at Yale heard this rumor and looked at the sequence of amino acids that make up coronavirus spike protein and syncytin-1. They found no similarities between the two. Then they looked to see if blood from women who had recovered from COVID-19 (and had this coronavirus-related antibody) would react with syncytin-1. It did not.

Because there is currently no specific data on pregnant women, current recommendations are for each woman to talk to her doctor about COVID-19 vaccination. However, for almost all women, pregnant, breastfeeding, or otherwise, the risk of COVID-19 infection far outweighs any risk of vaccination.

 

Last update: January 28, 2020 8:00PM
Science review: ERS